List of Publications:
Research Papers:-
1. Khan HY, Zubair H, Faisal M, Ullah MF, Farhan M, Sarkar FH, Ahmad A, Hadi SM. Plant Polyphenol induced cell death in human cancer cells involves mobilization of intracellular copper ions and reactive oxygen species generation: a mechanism for cancer chemopreventive action. Molecular Nutrition & Food Research, 2014; 58(3): 437-46. (Impact Factor = 4.31)
2. Khan HY, Orimo A. Transforming growth factor-β: Guardian of catabolic metabolism in carcinoma-associated fibroblasts. Cell Cycle, 2012; 11(23): 4302-3. (Impact Factor = 5.24)
3. HY Khan, H Zubair, MF Ullah, A Ahmad, SM Hadi. A prooxidant mechanism for the anticancer and chemopreventive properties of plant polyphenols. Curr Drug Targets, 2012; 13(14): 1738-49. (Impact Factor = 3.85)
4. Khan HY, Zubair H, Ullah MF, Ahmad A, Hadi SM. Oral administration of copper to rats leads to increased lymphocyte cellular DNA degradation by dietary polyphenols: implications for a cancer preventive mechanism. Biometals, 2011; 24: 1169-1178. (Impact Factor = 3.28)
5. Zubair H, Khan HY, Sohail A, Azim S, Ullah MF, Ahmad A, Sarkar FH, Hadi SM. Redox cycling of endogenous copper by thymoquinone leads to ROS-mediated DNA breakage and consequent cell death: putative anticancer mechanism of antioxidants. Cell Death & Disease, 2013; DOI: 10.1038/cddis.2013.172. (Impact Factor = 6.04)
6. H Zubair, HY Khan, MF Ullah, A Ahmad, D Wu, SM Hadi. Apogossypolone, derivative of gossypol, mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage. Eur J Pharm Sci, 2012; 47: 280-286. (Impact Factor = 2.99)
7. Ullah MF, Khan HY, Zubair H, Shamim U, Hadi SM. The antioxidant ascorbic acid mobilizes nuclear copper leading to a prooxidant cellular DNA breakage: Implications for chemotherapeutic action against cancer. Cancer Chemotherapy & Pharmacology, 2010; 67: 103-110. (Impact Factor = 2.8)
8. Zubair H, Khan HY, Arif H, Farhan M, Ullah MF, Ahmad A, Sarkar FH, Hadi SM. Targeting elevated levels of copper in cancer cells by gossypol and apoG2 for the treatment of cancer by the generation of reactive oxygen species. (Under Review)
9. Ullah MF, Ahmad A, Khan HY, Zubair H, Sarkar FH, Hadi SM. The prooxidant action of dietary antioxidants leading to cellular DNA breakage and anticancer effects: Implications for chemotherapeutic action against cancer. Cell Biochemistry & Biophysics, 2013; 67: 431-438. (Impact Factor = 1.91)
10. Suhail N, Bilal N, Khan HY, Hasan S, Sharma S, Khan F, Mansoor T, Banu N. Effect of vitamins C and E on antioxidant status of breast-cancer patients undergoing chemotherapy. Journal of Clinical Pharmacy and Therapeutics, 2012; 37:22-26. (Impact Factor = 2.1)
11. A Ahmad, MF Ullah, HY Khan, H Zubair, Y Li, B Bao, Zhiwei Wang, SM Hadi and FH Sarkar. DNA Damage Response in Cancer Progression and Drug Resistance. (Communicated; Under review).
12. Ullah MF, Ahmad A, Zubair H, Khan HY, Wang Z, Sarkar FH, Hadi SM. Soy isoflavone genistein induces cell death in breast cancer cells through mobilization of endogenous copper ions and generation of reactive oxygen species. Molecular Nutrition & Food Research, 2011; 55: 553-559. (Impact Factor = 4.31)
13. Hadi SM, Ullah MF, Azmi AS, Ahmad A, Shamim U, Zubair H, Khan HY. Resveratrol mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage: A putative mechanism for chemoprevention of cancer. Pharmaceutical Research, 2010; 27: 979-988. (Impact Factor = 4.74)
1. Ullah MF, Zubair H, Khan HY, Hadi SM. Isoflavone in chemoprevention of cancer. In Frank Columbus (ed:) Isoflavones: Biosynthesis, Occurrence and Health Effects; Nova Science, New York 2010, p271-284.
2. Zubair H, Ullah MF, Khan HY, Sarkar FH, Ahmad A, Hadi SM. Soy isoflavone genistein in cancer chemoprevention: Role of endogenous copper and involvement of reactive oxygen species. In Soy: Nutrition, Consumption and Health; Nova Science, New York 2013, p333-344.
3. MF Ullah, SH Bhat, E Hussain, F Abu-Duhier, HY Khan, M Aatif, A Ahmad, SM Hadi. Dietary phenolics as cancer chemopreventive nutraceuticals: a promising paradigm. In Atta-ur-Rahman / M. Iqbal Choudhary (Eds.): Frontiers in Anti-cancer Drug Discovery; Bentham Science Publishers 2013, 2, 32-92.
Conference Proceedings:-
1. Husain Y. Khan, Haseeb Zubair, Mohd. F. Ullah and Sheikh M. Hadi. A prooxidant mechanism of dietary polyphenols in cancer chemoprevention. Polyphenols Communications 2010, Vol. 1, p 28-29.
2. Zubair H, Khan HY, Ullah MF, Hadi SM. A prooxidant based anticancer mechanism of plant derived polyphenolic nutraceuticals. FASEB J. 2011, 25, 979.1.